The majority of asthmatic subjects with FeNO ≥70 ppb exhibited high E/ I MF levels in all lung fields (excluding the trachea) and V 50%pred <80%, suggesting inflammation throughout the airway. The left anterior chest and left posterior lower recording positions were associated with the best correlations (forced expiratory volume in 1 second/forced vital capacity: r=–0.55 and r=–0.58 logPC 20: r=–0.46 and r=–0.45 and FeNO: r=0.42 and r=0.46, respectively).
#BRONCHIAL BREATH SOUNDS PC#
Results: The E/ I data in the frequency range of 100–400 Hz ( E/ I low frequency, E/ I mid frequency ) were better correlated with the spirometry, PC 20, and FeNO values than were the I SPL or E SPL data. The data were analyzed for potential correlation with spirometry, airway hyperresponsiveness (PC 20), and fractional exhaled nitric oxide (FeNO). Inspiration sound pressure level ( I SPL), expiration sound pressure level ( E SPL), and the expiration-to-inspiration sound pressure ratio ( E/ I) were calculated in 6 frequency bands. Patients and methods: Breath sounds were recorded at 7 points on the body surface of 22 asthmatic subjects. We performed LSA at 7 points to examine whether the technique could identify the location of airway inflammation in patients with asthma. Purpose: Airway inflammation can be detected by lung sound analysis (LSA) at a single point in the posterior lower lung field. Terufumi Shimoda, 1 Yasushi Obase, 2 Yukio Nagasaka, 3 Hiroshi Nakano, 1 Akiko Ishimatsu, 1 Reiko Kishikawa, 1 Tomoaki Iwanaga 1ġClinical Research Center, Fukuoka National Hospital, Fukuoka, 2Second Department of Internal Medicine, School of Medicine, Nagasaki University, Nagasaki, 3Kyoto Respiratory Center, Otowa Hospital, Kyoto, Japan
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