
Conversely, foods that alkalinize the urine, such as beets, dairy products, kale, spinach may slightly slow urinary excretion of amphetamines. Foods that acidify the urine, such as cranberry juice, orange juice, or those that contain vitamin C (ascorbic acid) may increase amphetamine renal excretion.

In addition, the excretion of amphetamines is increased in acidic urine and decreased in alkaline urine. To ensure proper absorption, it may be prudent for the patient to avoid citrus fruits and citrus juices 1 hour before a dose, at the time of dosing, and for the 1 hour following a dose. However, certain gastrointestinal acidifying agents (e.g., certain fruit juices, etc.) can lower the oral absorption of amphetamines.

Notes for Professionals: In general, food does not significantly interact with the amphetamine stimulants, a dose may be taken with or without food.Taking a high amount of caffeine can increase the risk of irritability, nausea, nervousness, palpitations, problems with sleep (insomnia), rapid heartbeat, or other side effects. You may need to limit caffeine intake (food examples: coffee, teas, colas, and chocolate) while taking this medicine.

Acidic juices, like citrus juices (examples: orange juice, grapefruit juice) may decrease the absorption of this medication and are best avoided during the 1 hour before a dose, at the time of dosing, and for 1 hour after taking a dose.
